Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM40439
Substrate
n/a
Meas. Tech.
Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay Counterscreen Against Formyl Peptide Receptor-Like-1 (FPRL1)
IC50
>66700±n/a nM
Citation
 PubChem, PC Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay Counterscreen Against Formyl Peptide Receptor-Like-1 (FPRL1)  PubChem Bioassay (2007)[AID] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM40439
Synonyms:
(4E)-5-(4-bromophenyl)-1-(morpholin-4-ylmethyl)-4-[oxidanyl(phenyl)methylidene]pyrrolidine-2,3-dione | (4E)-5-(4-bromophenyl)-4-[hydroxy(phenyl)methylene]-1-(morpholinomethyl)pyrrolidine-2,3-quinone | (4E)-5-(4-bromophenyl)-4-[hydroxy(phenyl)methylidene]-1-(4-morpholinylmethyl)pyrrolidine-2,3-dione | (4E)-5-(4-bromophenyl)-4-[hydroxy(phenyl)methylidene]-1-(morpholin-4-ylmethyl)pyrrolidine-2,3-dione | UNM000003599401 | cid_5291891
Type:
Small organic molecule
Emp. Form.:
C22H21BrN2O4
Mol. Mass.:
457.317
SMILES:
Brc1ccc(cc1)C1C(C(=O)c2ccccc2)C(=O)C(=O)N1CN1CCOCC1
Structure:
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