Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM30999
Substrate
n/a
Meas. Tech.
S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E Agonists
EC50
>40000±n/a nM
Citation
 PubChem, PC S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E Agonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM30999
Synonyms:
MLS000031858 | N-(4-Ethyl-phenyl)-2-(2-methylsulfanyl-benzoimidazol-1-yl)-acetamide | N-(4-ethylphenyl)-2-(2-methylsulfanylbenzimidazol-1-yl)acetamide | N-(4-ethylphenyl)-2-(2-methylsulfanylbenzimidazol-1-yl)ethanamide | N-(4-ethylphenyl)-2-[2-(methylthio)-1-benzimidazolyl]acetamide | N-(4-ethylphenyl)-2-[2-(methylthio)benzimidazol-1-yl]acetamide | SMR000012737 | cid_644926
Type:
Small organic molecule
Emp. Form.:
C18H19N3OS
Mol. Mass.:
325.428
SMILES:
CCc1ccc(NC(=O)Cn2c(SC)nc3ccccc23)cc1
Structure:
Search PDB for entries with ligand similarity: