Reaction Details Report a problem with these data
Target
Estrogen receptor
Ligand
BDBM40484
Substrate
n/a
Meas. Tech.
Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation
EC50
9999000±n/a nM
Citation
 PubChem, PC Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
Estrogen receptor
Synonyms:
ER | ER-alpha | ESR | ESR1 | ESR1_HUMAN | Estradiol receptor | Estrogen receptor | Estrogen receptor (ER alpha) | Estrogen receptor (ER-alpha) | Estrogen receptor alpha (ER alpha) | Estrogen receptor alpha (ER) | NR3A1 | Nuclear receptor subfamily 3 group A member 1
Type:
Protein
Mol. Mass.:
66230.44
Organism:
Homo sapiens (Human)
Description:
P03372
Residue:
595
Sequence:
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
  
Inhibitor
Name:
BDBM40484
Synonyms:
2-Oxo-2H-chromene-3-carboxylic acid furan-2-ylmethyl-thiophen-2-ylmethyl-amide | MLS000033352 | N-(2-furanylmethyl)-2-oxo-N-(thiophen-2-ylmethyl)-1-benzopyran-3-carboxamide | N-(2-furfuryl)-2-keto-N-(2-thenyl)chromene-3-carboxamide | N-(furan-2-ylmethyl)-2-oxidanylidene-N-(thiophen-2-ylmethyl)chromene-3-carboxamide | N-(furan-2-ylmethyl)-2-oxo-N-(thiophen-2-ylmethyl)chromene-3-carboxamide | SMR000002086 | cid_650849
Type:
Small organic molecule
Emp. Form.:
C20H15NO4S
Mol. Mass.:
365.402
SMILES:
O=C(N(Cc1ccco1)Cc1cccs1)c1cc2ccccc2oc1=O
Structure:
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