Reaction Details Report a problem with these data
Target
Estrogen receptor
Ligand
BDBM40558
Substrate
n/a
Meas. Tech.
Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation
EC50
9999000±n/a nM
Citation
 PubChem, PC Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
Estrogen receptor
Synonyms:
ER | ER-alpha | ESR | ESR1 | ESR1_HUMAN | Estradiol receptor | Estrogen receptor | Estrogen receptor (ER alpha) | Estrogen receptor (ER-alpha) | Estrogen receptor alpha (ER alpha) | Estrogen receptor alpha (ER) | NR3A1 | Nuclear receptor subfamily 3 group A member 1
Type:
Protein
Mol. Mass.:
66230.44
Organism:
Homo sapiens (Human)
Description:
P03372
Residue:
595
Sequence:
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
  
Inhibitor
Name:
BDBM40558
Synonyms:
4-(4-Methoxy-phenyl)-2-methyl-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile | 4-(4-methoxyphenyl)-2-methyl-5-oxidanylidene-indeno[1,2-b]pyridine-3-carbonitrile | 4-(4-methoxyphenyl)-2-methyl-5-oxo-3-indeno[1,2-b]pyridinecarbonitrile | 4-(4-methoxyphenyl)-2-methyl-5-oxoindeno[1,2-b]pyridine-3-carbonitrile | 5-keto-4-(4-methoxyphenyl)-2-methyl-indeno[1,2-b]pyridine-3-carbonitrile | MLS000554940 | SMR000147057 | cid_947086
Type:
Small organic molecule
Emp. Form.:
C21H14N2O2
Mol. Mass.:
326.3481
SMILES:
COc1ccc(cc1)-c1c2C(=O)c3ccccc3-c2nc(C)c1C#N
Structure:
Search PDB for entries with ligand similarity: