Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 4 group A member 1
Ligand
BDBM31764
Substrate
n/a
Meas. Tech.
High Throughput Fluorescence Polarization Screen for Bcl-B Phenotype Converters
IC50
12477±901 nM
Citation
 PubChem, PC High Throughput Fluorescence Polarization Screen for Bcl-B Phenotype Converters PubChem Bioassay (2008)[AID] 
Target
Name:
Nuclear receptor subfamily 4 group A member 1
Synonyms:
GFRP1 | HMR | NAK1 | NR4A1 | NR4A1_HUMAN | nuclear receptor subfamily 4, group A, member 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
64467.13
Organism:
Homo sapiens (Human)
Description:
gi_27894344
Residue:
598
Sequence:
MPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAPTALPSFSTFMDGYTGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF
  
Inhibitor
Name:
BDBM31764
Synonyms:
MLS-0005454.0001 | N-(5-amyl-1,3,4-thiadiazol-2-yl)-2-(2-thienyl)acetamide | N-(5-pentyl-1,3,4-thiadiazol-2-yl)-2-thiophen-2-yl-ethanamide | N-(5-pentyl-1,3,4-thiadiazol-2-yl)-2-thiophen-2-ylacetamide | cid_2207086
Type:
Small organic molecule
Emp. Form.:
C13H17N3OS2
Mol. Mass.:
295.424
SMILES:
CCCCCc1nnc(NC(=O)Cc2cccs2)s1
Structure:
Search PDB for entries with ligand similarity: