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Target
Complement C1s subcomponent
Ligand
BDBM40891
Substrate
n/a
Meas. Tech.
Complement factor C1s IC50 from mixture screen
IC50
>50000±0 nM
Citation
 PubChem, PC Complement factor C1s IC50 from mixture screen PubChem Bioassay (2008)[AID] 
Target
Name:
Complement C1s subcomponent
Synonyms:
C1 esterase | C1S | C1S_HUMAN | Complement C1s | Complement C1s subcomponent | Complement C1s subcomponent heavy chain | Complement C1s subcomponent light chain | Complement component 1 subcomponent s | Trypsin | complement component 1, s subcomponent
Type:
Protein
Mol. Mass.:
76657.91
Organism:
Homo sapiens (Human)
Description:
P09871
Residue:
688
Sequence:
MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTYGLYTRVKNYVDWIMKTMQENSTPRED
  
Inhibitor
Name:
BDBM40891
Synonyms:
4-butyl-3-(5-chloranyl-2-methoxy-phenyl)-1H-1,2,4-triazole-5-thione | 4-butyl-3-(5-chloro-2-methoxy-phenyl)-1H-1,2,4-triazole-5-thione | 4-butyl-3-(5-chloro-2-methoxyphenyl)-1H-1,2,4-triazole-5-thione | 4-butyl-5-(5-chloro-2-methoxyphenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione | MLS000050054 | SMR000077066 | cid_2210728
Type:
Small organic molecule
Emp. Form.:
C13H16ClN3OS
Mol. Mass.:
297.804
SMILES:
CCCCn1c(n[nH]c1=S)-c1cc(Cl)ccc1OC
Structure:
Search PDB for entries with ligand similarity: