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Target
Complement C1s subcomponent
Ligand
BDBM40902
Substrate
n/a
Meas. Tech.
Complement factor C1s IC50 from mixture screen
IC50
>50000±0 nM
Citation
 PubChem, PC Complement factor C1s IC50 from mixture screen PubChem Bioassay (2008)[AID] 
Target
Name:
Complement C1s subcomponent
Synonyms:
C1 esterase | C1S | C1S_HUMAN | Complement C1s | Complement C1s subcomponent | Complement C1s subcomponent heavy chain | Complement C1s subcomponent light chain | Complement component 1 subcomponent s | Trypsin | complement component 1, s subcomponent
Type:
Protein
Mol. Mass.:
76657.91
Organism:
Homo sapiens (Human)
Description:
P09871
Residue:
688
Sequence:
MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTYGLYTRVKNYVDWIMKTMQENSTPRED
  
Inhibitor
Name:
BDBM40902
Synonyms:
MLS000088961 | N-(1,3-benzothiazol-2-yl)-2-methoxy-5-(4-morpholinylsulfonyl)benzamide | N-(1,3-benzothiazol-2-yl)-2-methoxy-5-morpholin-4-ylsulfonyl-benzamide | N-(1,3-benzothiazol-2-yl)-2-methoxy-5-morpholin-4-ylsulfonylbenzamide | N-(1,3-benzothiazol-2-yl)-2-methoxy-5-morpholinosulfonyl-benzamide | N-1,3-benzothiazol-2-yl-2-methoxy-5-(4-morpholinylsulfonyl)benzamide | SMR000073226 | cid_1540788
Type:
Small organic molecule
Emp. Form.:
C19H19N3O5S2
Mol. Mass.:
433.501
SMILES:
COc1ccc(cc1C(=O)Nc1nc2ccccc2s1)S(=O)(=O)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: