Reaction Details Report a problem with these data
Target
Complement C1s subcomponent
Ligand
BDBM40926
Substrate
n/a
Meas. Tech.
Complement factor C1s IC50 from mixture screen
IC50
>50000±0 nM
Citation
 PubChem, PC Complement factor C1s IC50 from mixture screen PubChem Bioassay (2008)[AID] 
Target
Name:
Complement C1s subcomponent
Synonyms:
C1 esterase | C1S | C1S_HUMAN | Complement C1s | Complement C1s subcomponent | Complement C1s subcomponent heavy chain | Complement C1s subcomponent light chain | Complement component 1 subcomponent s | Trypsin | complement component 1, s subcomponent
Type:
Protein
Mol. Mass.:
76657.91
Organism:
Homo sapiens (Human)
Description:
P09871
Residue:
688
Sequence:
MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTYGLYTRVKNYVDWIMKTMQENSTPRED
  
Inhibitor
Name:
BDBM40926
Synonyms:
(5Z)-5-(1-butyl-2-keto-indolin-3-ylidene)-2-piperidino-2-thiazolin-4-one | (5Z)-5-(1-butyl-2-oxidanylidene-indol-3-ylidene)-2-piperidin-1-yl-1,3-thiazol-4-one | (5Z)-5-(1-butyl-2-oxo-3-indolylidene)-2-(1-piperidinyl)-4-thiazolone | (5Z)-5-(1-butyl-2-oxoindol-3-ylidene)-2-piperidin-1-yl-1,3-thiazol-4-one | MLS000111979 | SMR000107897 | cid_1905581
Type:
Small organic molecule
Emp. Form.:
C20H23N3O2S
Mol. Mass.:
369.481
SMILES:
CCCCN1C(=O)\C(=C2/SC(=NC2=O)N2CCCCC2)c2ccccc12 |c:10|
Structure:
Search PDB for entries with ligand similarity: