Reaction Details Report a problem with these data
Target
Cathepsin B
Ligand
BDBM32768
Substrate
n/a
Meas. Tech.
Cathepsin B dose-response confirmation
IC50
38470.6±1512.3 nM
Citation
 PubChem, PC Cathepsin B dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin B
Synonyms:
APP secretase | APPS | CATB_HUMAN | CPSB | CTSB | Cathepsin B heavy chain | Cathepsin B light chain | Cathepsin B1
Type:
Enzyme
Mol. Mass.:
37819.69
Organism:
Homo sapiens (Human)
Description:
gi_63102437
Residue:
339
Sequence:
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
  
Inhibitor
Name:
BDBM32768
Synonyms:
2-furancarboxylic acid [2-(2-furanyl)-4-(phenyliminomethyl)-5-oxazolyl] ester | MLS000036330 | SMR000041595 | [2-(furan-2-yl)-4-(phenyliminomethyl)-1,3-oxazol-5-yl] furan-2-carboxylate | cid_660829 | furan-2-carboxylic acid [2-(2-furyl)-4-(phenyliminomethyl)oxazol-5-yl] ester
Type:
Small organic molecule
Emp. Form.:
C19H12N2O5
Mol. Mass.:
348.309
SMILES:
O=C(Oc1oc(nc1\C=N\c1ccccc1)-c1ccco1)c1ccco1
Structure:
Search PDB for entries with ligand similarity: