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Target
Cathepsin B
Ligand
BDBM41116
Substrate
n/a
Meas. Tech.
Cathepsin B dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin B dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin B
Synonyms:
APP secretase | APPS | CATB_HUMAN | CPSB | CTSB | Cathepsin B heavy chain | Cathepsin B light chain | Cathepsin B1
Type:
Enzyme
Mol. Mass.:
37819.69
Organism:
Homo sapiens (Human)
Description:
gi_63102437
Residue:
339
Sequence:
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
  
Inhibitor
Name:
BDBM41116
Synonyms:
4-(2-methoxyanilino)-4-oxobutanoic acid | 4-[(2-methoxyphenyl)amino]-4-oxidanylidene-butanoic acid | 4-[(2-methoxyphenyl)amino]-4-oxobutanoic acid | 4-keto-4-(o-anisidino)butyric acid | MLS000060916 | SMR000069144 | cid_693069
Type:
Small organic molecule
Emp. Form.:
C11H13NO4
Mol. Mass.:
223.2252
SMILES:
COc1ccccc1NC(=O)CCC(O)=O
Structure:
Search PDB for entries with ligand similarity: