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Target
Procathepsin L
Ligand
BDBM41130
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin L dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM41130
Synonyms:
2-(3-Methoxy-phenylamino)-3-thiophen-2-ylmethyl-3,5-dihydro-imidazol-4-one | 2-(3-methoxyanilino)-1-(thiophen-2-ylmethyl)-4H-imidazol-5-one;hydrochloride | 2-(m-anisidino)-3-(2-thenyl)-2-imidazolin-4-one;hydrochloride | 2-[(3-methoxyphenyl)amino]-1-(thiophen-2-ylmethyl)-4H-imidazol-5-one;hydrochloride | MLS000035059 | SMR000005621 | cid_6602585
Type:
Small organic molecule
Emp. Form.:
C15H15N3O2S
Mol. Mass.:
301.364
SMILES:
COc1cccc(c1)N=C1NCC(=O)N1Cc1cccs1 |w:8.8|
Structure:
Search PDB for entries with ligand similarity: