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Target
Procathepsin L
Ligand
BDBM41160
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin L dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM41160
Synonyms:
2-(1H-Benzoimidazol-2-ylsulfanyl)-N-(2-piperidin-1-yl-ethyl)-acetamide | 2-(1H-benzimidazol-2-ylsulfanyl)-N-(2-piperidin-1-ylethyl)acetamide | 2-(1H-benzimidazol-2-ylsulfanyl)-N-(2-piperidin-1-ylethyl)ethanamide | 2-(1H-benzimidazol-2-ylthio)-N-(2-piperidinoethyl)acetamide | 2-(1H-benzimidazol-2-ylthio)-N-[2-(1-piperidinyl)ethyl]acetamide | MLS000085305 | SMR000020043 | cid_752452
Type:
Small organic molecule
Emp. Form.:
C16H22N4OS
Mol. Mass.:
318.437
SMILES:
O=C(CSc1nc2ccccc2[nH]1)NCCN1CCCCC1
Structure:
Search PDB for entries with ligand similarity: