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Target
Procathepsin L
Ligand
BDBM41163
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin L dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM41163
Synonyms:
3-keto-2-pyrrolidino-4H-1,4-benzothiazine-6-carboxylic acid methyl ester | 3-oxo-2-(1-pyrrolidinyl)-4H-1,4-benzothiazine-6-carboxylic acid methyl ester | MLS000096013 | SMR000031561 | cid_3242193 | methyl 3-oxidanylidene-2-pyrrolidin-1-yl-4H-1,4-benzothiazine-6-carboxylate | methyl 3-oxo-2-pyrrolidin-1-yl-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate | methyl 3-oxo-2-pyrrolidin-1-yl-4H-1,4-benzothiazine-6-carboxylate
Type:
Small organic molecule
Emp. Form.:
C14H16N2O3S
Mol. Mass.:
292.353
SMILES:
COC(=O)c1ccc2SC(N3CCCC3)C(=O)Nc2c1
Structure:
Search PDB for entries with ligand similarity: