Reaction Details Report a problem with these data
Target
Procathepsin L
Ligand
BDBM35520
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response confirmation
IC50
1868.41±323.007 nM
Citation
 PubChem, PC Cathepsin L dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM35520
Synonyms:
4-(4-morpholinyl)-6-(1-piperidinyl)-1,3,5-triazine-2-carbonitrile | 4-morpholin-4-yl-6-piperidin-1-yl-1,3,5-triazine-2-carbonitrile | 4-morpholino-6-piperidino-s-triazine-2-carbonitrile | MLS000099932 | SMR000081092 | cid_729563
Type:
Small organic molecule
Emp. Form.:
C13H18N6O
Mol. Mass.:
274.3216
SMILES:
N#Cc1nc(nc(n1)N1CCOCC1)N1CCCCC1
Structure:
Search PDB for entries with ligand similarity: