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Target
Procathepsin L
Ligand
BDBM41180
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin L dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM41180
Synonyms:
4-[[1-(4-fluorophenyl)sulfonylpipecoloyl]amino]piperidine-1-carboxylic acid ethyl ester | 4-[[[1-(4-fluorophenyl)sulfonyl-2-piperidinyl]-oxomethyl]amino]-1-piperidinecarboxylic acid ethyl ester | MLS000116149 | SMR000093130 | cid_5309079 | ethyl 4-[[1-(4-fluorophenyl)sulfonylpiperidin-2-yl]carbonylamino]piperidine-1-carboxylate | ethyl 4-[[1-(4-fluorophenyl)sulfonylpiperidine-2-carbonyl]amino]piperidine-1-carboxylate
Type:
Small organic molecule
Emp. Form.:
C20H28FN3O5S
Mol. Mass.:
441.517
SMILES:
CCOC(=O)N1CCC(CC1)NC(=O)C1CCCCN1S(=O)(=O)c1ccc(F)cc1
Structure:
Search PDB for entries with ligand similarity: