Reaction Details Report a problem with these data
Target
Procathepsin L
Ligand
BDBM41189
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response confirmation
IC50
26953.1±14154.97 nM
Citation
 PubChem, PC Cathepsin L dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM41189
Synonyms:
4-(methanesulfonamido)-N-p-phenetyl-benzenesulfonamide | MLS000113673 | N-(4-ethoxyphenyl)-4-(methanesulfonamido)benzenesulfonamide | N-(4-ethoxyphenyl)-4-(methylsulfonylamino)benzenesulfonamide | SMR000109567 | cid_1315081
Type:
Small organic molecule
Emp. Form.:
C15H18N2O5S2
Mol. Mass.:
370.444
SMILES:
CCOc1ccc(NS(=O)(=O)c2ccc(NS(C)(=O)=O)cc2)cc1
Structure:
Search PDB for entries with ligand similarity: