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Target
Cathepsin S
Ligand
BDBM41284
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM41284
Synonyms:
2-furanyl-[4-[(4-methoxyphenyl)methyl]-1-piperazinyl]methanone | 2-furyl-(4-p-anisylpiperazino)methanone | Furan-2-yl-[4-(4-methoxy-benzyl)-piperazin-1-yl]-methanone | MLS000029346 | SMR000009845 | cid_648203 | furan-2-yl-[4-[(4-methoxyphenyl)methyl]piperazin-1-yl]methanone
Type:
Small organic molecule
Emp. Form.:
C17H20N2O3
Mol. Mass.:
300.3523
SMILES:
COc1ccc(CN2CCN(CC2)C(=O)c2ccco2)cc1
Structure:
Search PDB for entries with ligand similarity: