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Target
Cathepsin S
Ligand
BDBM41292
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM41292
Synonyms:
1-N-cyclohexyl-2-N-[4-(tetrazol-1-yl)phenyl]pyrrolidine-1,2-dicarboxamide | MLS000075127 | N-cyclohexyl-N'-[4-(tetrazol-1-yl)phenyl]pyrrolidine-1,2-dicarboxamide | N1-cyclohexyl-N2-[4-(1,2,3,4-tetrazol-1-yl)phenyl]pyrrolidine-1,2-dicarboxamide | N1-cyclohexyl-N2-[4-(1-tetrazolyl)phenyl]pyrrolidine-1,2-dicarboxamide | Pyrrolidine-1,2-dicarboxylic acid 1-cyclohexylamide 2-[(4-tetrazol-1-yl-phenyl)-amide] | SMR000006365 | cid_654097
Type:
Small organic molecule
Emp. Form.:
C19H25N7O2
Mol. Mass.:
383.4475
SMILES:
O=C(Nc1ccc(cc1)-n1cnnn1)C1CCCN1C(=O)NC1CCCCC1
Structure:
Search PDB for entries with ligand similarity: