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Target
Cathepsin S
Ligand
BDBM41294
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM41294
Synonyms:
2-[(3-allyl-4-keto-5,5-dimethyl-6H-benzo[h]quinazolin-2-yl)thio]acetonitrile | 2-[(5,5-dimethyl-4-oxidanylidene-3-prop-2-enyl-6H-benzo[h]quinazolin-2-yl)sulfanyl]ethanenitrile | 2-[(5,5-dimethyl-4-oxo-3-prop-2-enyl-6H-benzo[h]quinazolin-2-yl)sulfanyl]acetonitrile | 2-[(5,5-dimethyl-4-oxo-3-prop-2-enyl-6H-benzo[h]quinazolin-2-yl)thio]acetonitrile | MLS000030526 | SMR000038875 | cid_657963
Type:
Small organic molecule
Emp. Form.:
C19H19N3OS
Mol. Mass.:
337.439
SMILES:
CC1(C)Cc2ccccc2-c2nc(SCC#N)n(CC=C)c(=O)c12
Structure:
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