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Target
Cathepsin S
Ligand
BDBM41295
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
33067.8±1409.88 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM41295
Synonyms:
1-(benzylamino)-7-ethyl-3-piperidin-1-yl-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrile | 1-(benzylamino)-7-ethyl-3-piperidino-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrile | 7-ethyl-1-[(phenylmethyl)amino]-3-(1-piperidinyl)-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrile | 7-ethyl-1-[(phenylmethyl)amino]-3-piperidin-1-yl-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrile | MLS000071249 | SMR000039582 | cid_658540
Type:
Small organic molecule
Emp. Form.:
C23H29N5
Mol. Mass.:
375.5099
SMILES:
CCN1CCc2c(C1)c(NCc1ccccc1)nc(N1CCCCC1)c2C#N
Structure:
Search PDB for entries with ligand similarity: