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Target
Cathepsin S
Ligand
BDBM41312
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM41312
Synonyms:
2-(3-butoxyquinoxalin-2-yl)-2-(phenylsulfonyl)ethanenitrile | 2-(benzenesulfonyl)-2-(3-butoxy-2-quinoxalinyl)acetonitrile | 2-(benzenesulfonyl)-2-(3-butoxyquinoxalin-2-yl)acetonitrile | 2-besyl-2-(3-butoxyquinoxalin-2-yl)acetonitrile | MLS000048714 | SMR000060258 | cid_2998732
Type:
Small organic molecule
Emp. Form.:
C20H19N3O3S
Mol. Mass.:
381.448
SMILES:
CCCCOc1nc2ccccc2nc1C(C#N)S(=O)(=O)c1ccccc1
Structure:
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