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Target
Cathepsin S
Ligand
BDBM41321
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM41321
Synonyms:
3-(2,4-dimethoxyphenyl)-1H-quinazoline-2,4-dione | 3-(2,4-dimethoxyphenyl)-1H-quinazoline-2,4-quinone | 3-(2,4-dimethoxyphenyl)quinazoline-2,4(1H,3H)-dione | MLS000094682 | SMR000030235 | cid_3240110
Type:
Small organic molecule
Emp. Form.:
C16H14N2O4
Mol. Mass.:
298.2934
SMILES:
COc1ccc(c(OC)c1)-n1c(=O)[nH]c2ccccc2c1=O |(3.08,-3.94,;3.08,-2.4,;4.41,-1.63,;5.75,-2.4,;7.08,-1.63,;7.08,-.09,;5.75,.68,;5.75,2.22,;4.41,2.99,;4.41,-.09,;8.41,.68,;8.41,2.22,;7.08,2.99,;9.75,2.99,;11.08,2.22,;12.46,3.04,;13.85,2.25,;13.85,.65,;12.46,-.15,;11.08,.68,;9.75,-.09,;9.75,-1.63,)|
Structure:
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