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Target
Cathepsin S
Ligand
BDBM41324
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM41324
Synonyms:
(4E)-5-bromanyl-2-ethoxy-4-[(1,2,4-triazol-4-ylamino)methylidene]cyclohexa-2,5-dien-1-one | (4E)-5-bromo-2-ethoxy-4-[(1,2,4-triazol-4-ylamino)methylene]cyclohexa-2,5-dien-1-one | (4E)-5-bromo-2-ethoxy-4-[(1,2,4-triazol-4-ylamino)methylidene]-1-cyclohexa-2,5-dienone | (4E)-5-bromo-2-ethoxy-4-[(1,2,4-triazol-4-ylamino)methylidene]cyclohexa-2,5-dien-1-one | 5-bromo-2-ethoxy-4-[(E)-(4H-1,2,4-triazol-4-ylimino)methyl]phenol | MLS000089779 | SMR000024397 | cid_5771422
Type:
Small organic molecule
Emp. Form.:
C11H11BrN4O2
Mol. Mass.:
311.135
SMILES:
CCOc1cc(C=Nn2cnnc2)c(Br)cc1O |w:7.7|
Structure:
Search PDB for entries with ligand similarity: