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Target
Cathepsin S
Ligand
BDBM34492
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM34492
Synonyms:
2-[(1,3-dimethyl-2-oxidanylidene-benzimidazol-5-yl)methylidene]-5,7-dimethyl-[1,3]thiazolo[3,2-a]benzimidazol-1-one | 2-[(1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)methylene]-6,8-dimethyl[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one | 2-[(1,3-dimethyl-2-oxo-5-benzimidazolyl)methylidene]-5,7-dimethyl-1-thiazolo[3,2-a]benzimidazolone | 2-[(1,3-dimethyl-2-oxobenzimidazol-5-yl)methylidene]-5,7-dimethyl-[1,3]thiazolo[3,2-a]benzimidazol-1-one | 2-[(2-keto-1,3-dimethyl-benzimidazol-5-yl)methylene]-5,7-dimethyl-thiazolo[3,2-a]benzimidazol-1-one | MLS000061813 | SMR000070289 | cid_1361501
Type:
Small organic molecule
Emp. Form.:
C21H18N4O2S
Mol. Mass.:
390.458
SMILES:
Cc1cc(C)c2nc3sc(=Cc4ccc5n(C)c(=O)n(C)c5c4)c(=O)n3c2c1
Structure:
Search PDB for entries with ligand similarity: