Reaction Details Report a problem with these data
Target
Cathepsin S
Ligand
BDBM40654
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM40654
Synonyms:
6-[(dimethylsulfamoylamino)methyl]-3-methyl-imidazo[2,1-b][1,3]thiazole | 6-[(dimethylsulfamoylamino)methyl]-3-methyl-imidazo[2,1-b]thiazole | 6-[(dimethylsulfamoylamino)methyl]-3-methylimidazo[2,1-b][1,3]thiazole | 6-[(dimethylsulfamoylamino)methyl]-3-methylimidazo[2,1-b]thiazole | MLS000102779 | SMR000018219 | cid_5310188
Type:
Small organic molecule
Emp. Form.:
C9H14N4O2S2
Mol. Mass.:
274.363
SMILES:
CN(C)S(=O)(=O)NCc1cn2c(C)csc2n1
Structure:
Search PDB for entries with ligand similarity: