Reaction Details Report a problem with these data
Target
Cathepsin G
Ligand
BDBM36928
Substrate
n/a
Meas. Tech.
Cathepsin G dose-response confirmation
IC50
22603.1±2197.82 nM
Citation
 PubChem, PC Cathepsin G dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM36928
Synonyms:
MLS000083238 | N-[(1S)-3-methyl-1-[5-(2-methylbenzyl)sulfonyl-1,3,4-oxadiazol-2-yl]butyl]carbamic acid tert-butyl ester | N-[(1S)-3-methyl-1-[5-[(2-methylphenyl)methylsulfonyl]-1,3,4-oxadiazol-2-yl]butyl]carbamic acid tert-butyl ester | SMR000044673 | cid_663900 | tert-butyl N-[(1S)-3-methyl-1-[5-[(2-methylphenyl)methylsulfonyl]-1,3,4-oxadiazol-2-yl]butyl]carbamate
Type:
Small organic molecule
Emp. Form.:
C20H29N3O5S
Mol. Mass.:
423.526
SMILES:
CC(C)C[C@H](NC(=O)OC(C)(C)C)c1nnc(o1)S(=O)(=O)Cc1ccccc1C
Structure:
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