Reaction Details Report a problem with these data
Target
Cathepsin G
Ligand
BDBM41391
Substrate
n/a
Meas. Tech.
Cathepsin G dose-response confirmation
IC50
44400±0 nM
Citation
 PubChem, PC Cathepsin G dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM41391
Synonyms:
MLS000087058 | N-[1-(2-chlorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-5-(4-methoxyphenyl)isoxazole-3-carboxamide | N-[1-(2-chlorobenzyl)-3,5-dimethyl-pyrazol-4-yl]-5-(4-methoxyphenyl)isoxazole-3-carboxamide | N-[1-[(2-chlorophenyl)methyl]-3,5-dimethyl-4-pyrazolyl]-5-(4-methoxyphenyl)-3-isoxazolecarboxamide | N-[1-[(2-chlorophenyl)methyl]-3,5-dimethyl-pyrazol-4-yl]-5-(4-methoxyphenyl)-1,2-oxazole-3-carboxamide | N-[1-[(2-chlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-5-(4-methoxyphenyl)-1,2-oxazole-3-carboxamide | SMR000023281 | cid_3236272
Type:
Small organic molecule
Emp. Form.:
C23H21ClN4O3
Mol. Mass.:
436.891
SMILES:
COc1ccc(cc1)-c1cc(no1)C(=O)Nc1c(C)nn(Cc2ccccc2Cl)c1C
Structure:
Search PDB for entries with ligand similarity: