Reaction Details Report a problem with these data
Target
Cathepsin G
Ligand
BDBM41394
Substrate
n/a
Meas. Tech.
Cathepsin G dose-response confirmation
IC50
33023.9±777.673 nM
Citation
 PubChem, PC Cathepsin G dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM41394
Synonyms:
5-(2,5-dimethoxyphenyl)-N-[3,5-dimethyl-1-(phenylmethyl)-4-pyrazolyl]-3-isoxazolecarboxamide | 5-(2,5-dimethoxyphenyl)-N-[3,5-dimethyl-1-(phenylmethyl)pyrazol-4-yl]-1,2-oxazole-3-carboxamide | MLS000087188 | N-(1-benzyl-3,5-dimethyl-1H-pyrazol-4-yl)-5-(2,5-dimethoxyphenyl)isoxazole-3-carboxamide | N-(1-benzyl-3,5-dimethyl-pyrazol-4-yl)-5-(2,5-dimethoxyphenyl)isoxazole-3-carboxamide | N-(1-benzyl-3,5-dimethylpyrazol-4-yl)-5-(2,5-dimethoxyphenyl)-1,2-oxazole-3-carboxamide | SMR000023411 | cid_3236902
Type:
Small organic molecule
Emp. Form.:
C24H24N4O4
Mol. Mass.:
432.4718
SMILES:
COc1ccc(OC)c(c1)-c1cc(no1)C(=O)Nc1c(C)nn(Cc2ccccc2)c1C
Structure:
Search PDB for entries with ligand similarity: