Reaction Details Report a problem with these data
Target
Cathepsin G
Ligand
BDBM41397
Substrate
n/a
Meas. Tech.
Cathepsin G dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin G dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM41397
Synonyms:
3,4-dihydro-1H-isoquinolin-2-yl-(7-methoxy-4,5-dihydrobenz[g]indoxazen-3-yl)methanone | 3,4-dihydro-1H-isoquinolin-2-yl-(7-methoxy-4,5-dihydrobenzo[g][1,2]benzoxazol-3-yl)methanone | 3-(3,4-dihydroisoquinolin-2(1H)-ylcarbonyl)-7-methoxy-4,5-dihydronaphtho[2,1-d]isoxazole | MLS000087445 | SMR000023668 | cid_3238703
Type:
Small organic molecule
Emp. Form.:
C22H20N2O3
Mol. Mass.:
360.4058
SMILES:
COc1ccc2-c3onc(C(=O)N4CCc5ccccc5C4)c3CCc2c1
Structure:
Search PDB for entries with ligand similarity: