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Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM41609
Substrate
n/a
Meas. Tech.
Dose Response Cell Based Assay for Antagonists of the S1P2 Receptor
IC50
2652±n/a nM
Citation
 PubChem, PC Dose Response Cell Based Assay for Antagonists of the S1P2 Receptor PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM41609
Synonyms:
(4,5-dichloro-6-oxopyridazin-1-yl)methyl 4-methylbenzoate | 4-methylbenzoic acid (4,5-dichloro-6-keto-pyridazin-1-yl)methyl ester | 4-methylbenzoic acid (4,5-dichloro-6-oxo-1-pyridazinyl)methyl ester | MLS000546966 | SMR000180164 | [4,5-bis(chloranyl)-6-oxidanylidene-pyridazin-1-yl]methyl 4-methylbenzoate | [4,5-dichloro-6-oxo-1(6H)-pyridazinyl]methyl 4-methylbenzenecarboxylate | cid_1474465
Type:
Small organic molecule
Emp. Form.:
C13H10Cl2N2O3
Mol. Mass.:
313.136
SMILES:
Cc1ccc(cc1)C(=O)OCn1ncc(Cl)c(Cl)c1=O
Structure:
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