Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM41622
Substrate
n/a
Meas. Tech.
Dose Response Cell Based Assay for Antagonists of the S1P2 Receptor
IC50
>30000±n/a nM
Citation
 PubChem, PC Dose Response Cell Based Assay for Antagonists of the S1P2 Receptor PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM41622
Synonyms:
N-(4-fluorophenyl)-2-(2-thienyl)cinchoninamide | N-(4-fluorophenyl)-2-thiophen-2-yl-4-quinolinecarboxamide | N-(4-fluorophenyl)-2-thiophen-2-yl-quinoline-4-carboxamide | N-(4-fluorophenyl)-2-thiophen-2-ylquinoline-4-carboxamide | SR-01000412716-2 | cid_673633
Type:
Small organic molecule
Emp. Form.:
C20H13FN2OS
Mol. Mass.:
348.393
SMILES:
Fc1ccc(NC(=O)c2cc(nc3ccccc23)-c2cccs2)cc1
Structure:
Search PDB for entries with ligand similarity: