Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM30911
Substrate
n/a
Meas. Tech.
Dose Response Cell Based Assay for Agonists of the S1P2 Receptor
EC50
1988±n/a nM
Citation
 PubChem, PC Dose Response Cell Based Assay for Agonists of the S1P2 Receptor PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM30911
Synonyms:
7-(2-furoyloxy)-2-keto-chromene-3-carboxylic acid ethyl ester | 7-[2-furanyl(oxo)methoxy]-2-oxo-1-benzopyran-3-carboxylic acid ethyl ester | MLS000050094 | SMR000077133 | cid_733831 | ethyl 7-(2-furoyloxy)-2-oxo-2H-chromene-3-carboxylate | ethyl 7-(furan-2-carbonyloxy)-2-oxochromene-3-carboxylate | ethyl 7-(furan-2-ylcarbonyloxy)-2-oxidanylidene-chromene-3-carboxylate
Type:
Small organic molecule
Emp. Form.:
C17H12O7
Mol. Mass.:
328.273
SMILES:
CCOC(=O)c1cc2ccc(OC(=O)c3ccco3)cc2oc1=O
Structure:
Search PDB for entries with ligand similarity: