Reaction Details Report a problem with these data
Target
Bifunctional epoxide hydrolase 2
Ligand
BDBM41946
Substrate
n/a
Meas. Tech.
sEH_DR_Inh_Infinite200_Fluorescence_01072008
IC50
>10000±n/a nM
Citation
 PubChem, PC sEH_DR_Inh_Infinite200_Fluorescence_01072008 PubChem Bioassay (2008)[AID] 
Target
Name:
Bifunctional epoxide hydrolase 2
Synonyms:
Cytosolic epoxide hydrolase 2 | EBifunctional epoxide hydrolase 2 | EPHX2 | Epoxide hydratase | HYES_HUMAN | Lipid-phosphate phosphatase | Soluble epoxide hydrolase (sEH) | epoxide hydrolase 2, cytoplasmic
Type:
Enzyme
Mol. Mass.:
62613.07
Organism:
Homo sapiens (Human)
Description:
P34913
Residue:
555
Sequence:
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARNPPVVSKM
  
Inhibitor
Name:
BDBM41946
Synonyms:
3-(2-bromanyl-6-chloranyl-4-methyl-phenoxy)-N-(phenylmethyl)propan-1-amine;ethanedioic acid | 3-(2-bromo-6-chloro-4-methylphenoxy)-N-(phenylmethyl)-1-propanamine;oxalic acid | MLS000576317 | N-benzyl-3-(2-bromo-6-chloro-4-methylphenoxy)-1-propanamine oxalate | N-benzyl-3-(2-bromo-6-chloro-4-methylphenoxy)propan-1-amine;oxalic acid | SMR000197957 | benzyl-[3-(2-bromo-6-chloro-4-methyl-phenoxy)propyl]amine;oxalic acid | cid_2933964
Type:
Small organic molecule
Emp. Form.:
C17H19BrClNO
Mol. Mass.:
368.696
SMILES:
Cc1cc(Cl)c(OCCCNCc2ccccc2)c(Br)c1
Structure:
Search PDB for entries with ligand similarity: