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Target
Galanin receptor type 2
Ligand
BDBM41949
Substrate
n/a
Meas. Tech.
Dose Response cell-based high-throughput screening assay to identify agonists of galanin receptor 2 (GALR2)
EC50
45422±n/a nM
Citation
 PubChem, PC Dose Response cell-based high-throughput screening assay to identify agonists of galanin receptor 2 (GALR2) PubChem Bioassay (2008)[AID] 
Target
Name:
Galanin receptor type 2
Synonyms:
GALNR2 | GALR2 | GALR2_HUMAN | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galanin receptor type 2 (GAL2-R) (GALR2).
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41724.40
Organism:
Homo sapiens (Human)
Description:
Galanin R2 GALR2 HUMAN::O43603
Residue:
387
Sequence:
MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
  
Inhibitor
Name:
BDBM41949
Synonyms:
(E)-2-cyano-3-(1-phenyl-3-thiophen-2-yl-4-pyrazolyl)-N-prop-2-enyl-2-propenamide | (E)-2-cyano-3-(1-phenyl-3-thiophen-2-yl-pyrazol-4-yl)-N-prop-2-enyl-prop-2-enamide | (E)-2-cyano-3-(1-phenyl-3-thiophen-2-ylpyrazol-4-yl)-N-prop-2-enylprop-2-enamide | (E)-N-Allyl-2-cyano-3-(1-phenyl-3-thiophen-2-yl-1H-pyrazol-4-yl)-acrylamide | (E)-N-allyl-2-cyano-3-[1-phenyl-3-(2-thienyl)pyrazol-4-yl]acrylamide | MLS000588327 | SMR000212142 | cid_1902746
Type:
Small organic molecule
Emp. Form.:
C20H16N4OS
Mol. Mass.:
360.432
SMILES:
C=CCNC(=O)C(=C\c1cn(nc1-c1cccs1)-c1ccccc1)\C#N
Structure:
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