Reaction Details Report a problem with these data
Target
Bcl-2-related protein A1
Ligand
BDBM39127
Substrate
n/a
Meas. Tech.
In Vitro Bfl-1 Dose Response Fluorescence Polarization Assay for SAR Study
IC50
1630±150 nM
Citation
 PubChem, PC In Vitro Bfl-1 Dose Response Fluorescence Polarization Assay for SAR Study PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM39127
Synonyms:
1-[3,5-bis(chloranyl)phenyl]-3-chloranyl-4-morpholin-4-yl-pyrrole-2,5-dione | 3-chloro-1-(3,5-dichlorophenyl)-4-(4-morpholinyl)pyrrole-2,5-dione | 3-chloro-1-(3,5-dichlorophenyl)-4-morpholin-4-ylpyrrole-2,5-dione | 3-chloro-1-(3,5-dichlorophenyl)-4-morpholino-3-pyrroline-2,5-quinone | MLS-0067151.0001 | cid_1664243
Type:
Small organic molecule
Emp. Form.:
C14H11Cl3N2O3
Mol. Mass.:
361.608
SMILES:
ClC1=C(N2CCOCC2)C(=O)N(C1=O)c1cc(Cl)cc(Cl)c1 |c:1|
Structure:
Search PDB for entries with ligand similarity: