Reaction Details Report a problem with these data
Target
Bcl-2-related protein A1
Ligand
BDBM39154
Substrate
n/a
Meas. Tech.
In Vitro Bfl-1 Dose Response Fluorescence Polarization Assay for SAR Study
IC50
4950±810 nM
Citation
 PubChem, PC In Vitro Bfl-1 Dose Response Fluorescence Polarization Assay for SAR Study PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM39154
Synonyms:
3-chloranyl-1-(3,4-dichlorophenyl)-4-(4-phenylpiperazin-1-yl)pyrrole-2,5-dione | 3-chloro-1-(3,4-dichlorophenyl)-4-(4-phenyl-1-piperazinyl)pyrrole-2,5-dione | 3-chloro-1-(3,4-dichlorophenyl)-4-(4-phenylpiperazin-1-yl)-1H-pyrrole-2,5-dione | 3-chloro-1-(3,4-dichlorophenyl)-4-(4-phenylpiperazin-1-yl)pyrrole-2,5-dione | 3-chloro-1-(3,4-dichlorophenyl)-4-(4-phenylpiperazino)-3-pyrroline-2,5-quinone | CHEMBL1272155 | MLS-0090869.0001 | cid_1654287
Type:
Small organic molecule
Emp. Form.:
C20H16Cl3N3O2
Mol. Mass.:
436.719
SMILES:
ClC1=C(N2CCN(CC2)c2ccccc2)C(=O)N(C1=O)c1ccc(Cl)c(Cl)c1 |c:1|
Structure:
Search PDB for entries with ligand similarity: