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Target
Galanin receptor type 2
Ligand
BDBM37434
Substrate
n/a
Meas. Tech.
Dose Response cell-based high-throughput screening assay to identify antagonists of galanin receptor 2 (GALR2)
IC50
>42000±n/a nM
Citation
 PubChem, PC Dose Response cell-based high-throughput screening assay to identify antagonists of galanin receptor 2 (GALR2) PubChem Bioassay (2008)[AID] 
Target
Name:
Galanin receptor type 2
Synonyms:
GALNR2 | GALR2 | GALR2_HUMAN | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galanin receptor type 2 (GAL2-R) (GALR2).
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41724.40
Organism:
Homo sapiens (Human)
Description:
Galanin R2 GALR2 HUMAN::O43603
Residue:
387
Sequence:
MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
  
Inhibitor
Name:
BDBM37434
Synonyms:
2-[(1-bicyclo[2.2.1]hept-2-yl-1H-tetrazol-5-yl)thio]-N-4-quinolinylacetamide | 2-[1-(3-bicyclo[2.2.1]heptanyl)tetrazol-5-yl]sulfanyl-N-quinolin-4-ylacetamide | 2-[[1-(2-norbornyl)tetrazol-5-yl]thio]-N-(4-quinolyl)acetamide | 2-[[1-(3-bicyclo[2.2.1]heptanyl)-1,2,3,4-tetrazol-5-yl]sulfanyl]-N-quinolin-4-yl-ethanamide | 2-[[1-(3-bicyclo[2.2.1]heptanyl)-5-tetrazolyl]thio]-N-(4-quinolinyl)acetamide | MLS000066069 | SMR000079553 | cid_2967368
Type:
Small organic molecule
Emp. Form.:
C19H20N6OS
Mol. Mass.:
380.467
SMILES:
[H]C12CCC([H])(C1)C(C2)n1nnnc1SCC(=O)Nc1ccnc2ccccc12 |TLB:9:7:6:3.2|
Structure:
Search PDB for entries with ligand similarity: