Target
Galanin receptor type 2
Ligand
BDBM42045
Substrate
n/a
Meas. Tech.
Dose Response cell-based high-throughput screening assay to identify antagonists of galanin receptor 2 (GALR2)
IC50
14420±n/a nM
Citation
 PubChem, PC Dose Response cell-based high-throughput screening assay to identify antagonists of galanin receptor 2 (GALR2) PubChem Bioassay (2008)[AID] 
Target
Name:
Galanin receptor type 2
Synonyms:
GALNR2 | GALR2 | GALR2_HUMAN | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galanin receptor type 2 (GAL2-R) (GALR2).
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41724.40
Organism:
Homo sapiens (Human)
Description:
Galanin R2 GALR2 HUMAN::O43603
Residue:
387
Sequence:
MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
  
Inhibitor
Name:
BDBM42045
Synonyms:
MLS000554273 | S-[1-(1-acetylindol-3-yl)-2-nitroethyl] ethanethioate | S-[1-(1-ethanoylindol-3-yl)-2-nitro-ethyl] ethanethioate | SMR000146590 | Thioacetic acid S-[1-(1-acetyl-1H-indol-3-yl)-2-nitro-ethyl] ester | cid_3775080 | ethanethioic acid S-[1-(1-acetyl-3-indolyl)-2-nitroethyl] ester | ethanethioic acid S-[1-(1-acetylindol-3-yl)-2-nitro-ethyl] ester
Type:
Small organic molecule
Emp. Form.:
C14H14N2O4S
Mol. Mass.:
306.337
SMILES:
CC(=O)SC(C[N+]([O-])=O)c1cn(C(C)=O)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: