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Target
Galanin receptor type 2
Ligand
BDBM42055
Substrate
n/a
Meas. Tech.
Dose Response cell-based high-throughput screening assay to identify antagonists of galanin receptor 2 (GALR2)
IC50
>42000±n/a nM
Citation
 PubChem, PC Dose Response cell-based high-throughput screening assay to identify antagonists of galanin receptor 2 (GALR2) PubChem Bioassay (2008)[AID] 
Target
Name:
Galanin receptor type 2
Synonyms:
GALNR2 | GALR2 | GALR2_HUMAN | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galanin receptor type 2 (GAL2-R) (GALR2).
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41724.40
Organism:
Homo sapiens (Human)
Description:
Galanin R2 GALR2 HUMAN::O43603
Residue:
387
Sequence:
MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
  
Inhibitor
Name:
BDBM42055
Synonyms:
(E)-2-(1H-benzimidazol-2-yl)-3-(2-thienyl)acrylonitrile | (E)-2-(1H-benzimidazol-2-yl)-3-thiophen-2-yl-2-propenenitrile | (E)-2-(1H-benzimidazol-2-yl)-3-thiophen-2-yl-prop-2-enenitrile | (E)-2-(1H-benzimidazol-2-yl)-3-thiophen-2-ylprop-2-enenitrile | 2-(1H-Benzoimidazol-2-yl)-3-thiophen-2-yl-acrylonitrile | MLS000567024 | SMR000175048 | cid_5334847
Type:
Small organic molecule
Emp. Form.:
C14H9N3S
Mol. Mass.:
251.306
SMILES:
N#C\C(=C/c1cccs1)c1nc2ccccc2[nH]1
Structure:
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