Reaction Details Report a problem with these data
Target
Glyceraldehyde-3-phosphate dehydrogenase
Ligand
BDBM41998
Substrate
n/a
Meas. Tech.
GAPDH Dose Response Colorimetric Assay
IC50
15800±1830 nM
Citation
 PubChem, PC GAPDH Dose Response Colorimetric Assay PubChem Bioassay (2008)[AID] 
Target
Name:
Glyceraldehyde-3-phosphate dehydrogenase
Synonyms:
G3P_HUMAN | GAPD | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase liver | glyceraldehyde-3-phosphate dehydrogenase
Type:
PROTEIN
Mol. Mass.:
36060.86
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1511315
Residue:
335
Sequence:
MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE
  
Inhibitor
Name:
BDBM41998
Synonyms:
(9Z)-9-(3,3-dihydroxyprop-2-enylidene)-5,6-dihydroxy-xanthene-3,4-quinone | (9Z)-9-(3,3-dihydroxyprop-2-enylidene)-5,6-dihydroxyxanthene-3,4-dione | (9Z)-9-[3,3-bis(oxidanyl)prop-2-enylidene]-5,6-bis(oxidanyl)xanthene-3,4-dione | MLS-0111616.0001 | cid_5351983
Type:
Small organic molecule
Emp. Form.:
C16H10O7
Mol. Mass.:
314.2464
SMILES:
OC(=O)C=Cc1c2ccc(O)c(O)c2oc2c(O)c(=O)ccc12
Structure:
Search PDB for entries with ligand similarity: