Reaction Details Report a problem with these data
Target
Galanin receptor type 2
Ligand
BDBM37108
Substrate
n/a
Meas. Tech.
Dose response counterscreen for antagonists of galanin receptor 2 (GalR2): a cell-based high-throughput screening assay for inhibitors of beta-lactamase activity
IC50
>42000±n/a nM
Citation
 PubChem, PC Dose response counterscreen for antagonists of galanin receptor 2 (GalR2): a cell-based high-throughput screening assay for inhibitors of beta-lactamase activity PubChem Bioassay (2008)[AID] 
Target
Name:
Galanin receptor type 2
Synonyms:
GALNR2 | GALR2 | GALR2_HUMAN | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galanin receptor type 2 (GAL2-R) (GALR2).
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41724.40
Organism:
Homo sapiens (Human)
Description:
Galanin R2 GALR2 HUMAN::O43603
Residue:
387
Sequence:
MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
  
Inhibitor
Name:
BDBM37108
Synonyms:
5-bromanyl-N-(pyridin-4-ylmethyl)thiophene-2-sulfonamide | 5-bromo-N-(4-pyridinylmethyl)-2-thiophenesulfonamide | 5-bromo-N-(4-pyridylmethyl)thiophene-2-sulfonamide | 5-bromo-N-(pyridin-4-ylmethyl)-2-thiophenesulfonamide | 5-bromo-N-(pyridin-4-ylmethyl)thiophene-2-sulfonamide | MLS000063220 | SMR000074767 | cid_936105
Type:
Small organic molecule
Emp. Form.:
C10H9BrN2O2S2
Mol. Mass.:
333.225
SMILES:
Brc1ccc(s1)S(=O)(=O)NCc1ccncc1
Structure:
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