Reaction Details Report a problem with these data
Target
Galanin receptor type 2
Ligand
BDBM42043
Substrate
n/a
Meas. Tech.
Dose response counterscreen for antagonists of galanin receptor 2 (GalR2): a cell-based high-throughput screening assay for inhibitors of beta-lactamase activity
IC50
>42000±n/a nM
Citation
 PubChem, PC Dose response counterscreen for antagonists of galanin receptor 2 (GalR2): a cell-based high-throughput screening assay for inhibitors of beta-lactamase activity PubChem Bioassay (2008)[AID] 
Target
Name:
Galanin receptor type 2
Synonyms:
GALNR2 | GALR2 | GALR2_HUMAN | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galanin receptor type 2 (GAL2-R) (GALR2).
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41724.40
Organism:
Homo sapiens (Human)
Description:
Galanin R2 GALR2 HUMAN::O43603
Residue:
387
Sequence:
MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
  
Inhibitor
Name:
BDBM42043
Synonyms:
Adamantane-1-carboxylic acid (2-pyridin-3-yl-1H-benzoimidazol-5-yl)-amide | MLS000121596 | N-(2-pyridin-3-yl-3H-benzimidazol-5-yl)adamantane-1-carboxamide | N-[2-(3-pyridinyl)-3H-benzimidazol-5-yl]-1-adamantanecarboxamide | N-[2-(3-pyridyl)-3H-benzimidazol-5-yl]adamantane-1-carboxamide | SMR000118973 | cid_3147250
Type:
Small organic molecule
Emp. Form.:
C23H24N4O
Mol. Mass.:
372.4629
SMILES:
[H]C12CC3([H])CC([H])(C1)CC(C2)(C3)C(=O)Nc1ccc2nc([nH]c2c1)-c1cccnc1 |TLB:8:1:12:6.9.5,THB:2:1:9:3.12.5,2:3:9:1.11.8|
Structure:
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