Reaction Details Report a problem with these data
Target
Galanin receptor type 2
Ligand
BDBM42050
Substrate
n/a
Meas. Tech.
Dose response counterscreen for antagonists of galanin receptor 2 (GalR2): a cell-based high-throughput screening assay for inhibitors of beta-lactamase activity
IC50
>42000±n/a nM
Citation
 PubChem, PC Dose response counterscreen for antagonists of galanin receptor 2 (GalR2): a cell-based high-throughput screening assay for inhibitors of beta-lactamase activity PubChem Bioassay (2008)[AID] 
Target
Name:
Galanin receptor type 2
Synonyms:
GALNR2 | GALR2 | GALR2_HUMAN | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galanin receptor type 2 (GAL2-R) (GALR2).
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41724.40
Organism:
Homo sapiens (Human)
Description:
Galanin R2 GALR2 HUMAN::O43603
Residue:
387
Sequence:
MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
  
Inhibitor
Name:
BDBM42050
Synonyms:
1-(tosylmethyl)-1,2-dihydrothiazolo[3,2-a]benzimidazole | 1-[(4-methylphenyl)sulfonylmethyl]-1,2-dihydro-[1,3]thiazolo[3,2-a]benzimidazole | 1-[(4-methylphenyl)sulfonylmethyl]-1,2-dihydrothiazolo[3,2-a]benzimidazole | 3-(Toluene-4-sulfonylmethyl)-2,3-dihydro-benzo[4,5]imidazo[2,1-b]thiazole | MLS000558294 | SMR000178607 | cid_2955782
Type:
Small organic molecule
Emp. Form.:
C17H16N2O2S2
Mol. Mass.:
344.451
SMILES:
Cc1ccc(cc1)S(=O)(=O)CC1CSc2nc3ccccc3n12
Structure:
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