Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 4 group A member 1
Ligand
BDBM42093
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Dose Response Assay for TR3-Based Bcl-B Inhibitors
EC50
5410±7740 nM
Citation
 PubChem, PC Fluorescence Polarization Dose Response Assay for TR3-Based Bcl-B Inhibitors PubChem Bioassay (2008)[AID] 
Target
Name:
Nuclear receptor subfamily 4 group A member 1
Synonyms:
GFRP1 | HMR | NAK1 | NR4A1 | NR4A1_HUMAN | nuclear receptor subfamily 4, group A, member 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
64467.13
Organism:
Homo sapiens (Human)
Description:
gi_27894344
Residue:
598
Sequence:
MPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAPTALPSFSTFMDGYTGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF
  
Inhibitor
Name:
BDBM42093
Synonyms:
4-(4-nitrophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-6-carboxylic acid | BIM-0025520.P001 | cid_2854305
Type:
Small organic molecule
Emp. Form.:
C19H16N2O4
Mol. Mass.:
336.3413
SMILES:
OC(=O)c1cccc2C3C=CCC3C(Nc12)c1ccc(cc1)[N+]([O-])=O |c:9|
Structure:
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