Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 4 group A member 1
Ligand
BDBM42117
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Dose Response Assay for TR3-Based Bcl-B Inhibitors
EC50
620±220 nM
Citation
 PubChem, PC Fluorescence Polarization Dose Response Assay for TR3-Based Bcl-B Inhibitors PubChem Bioassay (2008)[AID] 
Target
Name:
Nuclear receptor subfamily 4 group A member 1
Synonyms:
GFRP1 | HMR | NAK1 | NR4A1 | NR4A1_HUMAN | nuclear receptor subfamily 4, group A, member 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
64467.13
Organism:
Homo sapiens (Human)
Description:
gi_27894344
Residue:
598
Sequence:
MPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAPTALPSFSTFMDGYTGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF
  
Inhibitor
Name:
BDBM42117
Synonyms:
2-(2,5-dimethyl-1-pyrrolyl)benzoic acid | 2-(2,5-dimethylpyrrol-1-yl)benzoic acid | BIM-0048144.P001 | cid_292956
Type:
Small organic molecule
Emp. Form.:
C13H13NO2
Mol. Mass.:
215.2478
SMILES:
Cc1ccc(C)n1-c1ccccc1C(O)=O |(10.11,1.55,;8.64,2.03,;8.17,3.49,;6.63,3.49,;6.15,2.03,;4.72,2.61,;7.4,1.13,;7.4,-.41,;8.73,-1.18,;8.73,-2.72,;7.4,-3.49,;6.06,-2.72,;6.06,-1.18,;4.55,-1.45,;4.02,-2.9,;3.56,-.27,)|
Structure:
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