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Target
Tyrosine-protein phosphatase YopH
Ligand
BDBM42189
Substrate
n/a
Meas. Tech.
YopH - IC50 determinations (10 point dose range)
IC50
>50000±n/a nM
Citation
 PubChem, PC YopH - IC50 determinations (10 point dose range) PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase YopH
Synonyms:
YOPH_YEREN | yop51 | yopH
Type:
PROTEIN
Mol. Mass.:
50951.99
Organism:
Yersinia enterocolitica
Description:
ChEMBL_965525
Residue:
468
Sequence:
MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
  
Inhibitor
Name:
BDBM42189
Synonyms:
1-(3-Chloro-4-methyl-benzenesulfonyl)-piperidine-3-carboxylic acid (furan-2-ylmethyl)-amide | 1-(3-chloranyl-4-methyl-phenyl)sulfonyl-N-(furan-2-ylmethyl)piperidine-3-carboxamide | 1-(3-chloro-4-methyl-phenyl)sulfonyl-N-(2-furfuryl)nipecotamide | 1-(3-chloro-4-methylphenyl)sulfonyl-N-(2-furanylmethyl)-3-piperidinecarboxamide | 1-(3-chloro-4-methylphenyl)sulfonyl-N-(furan-2-ylmethyl)piperidine-3-carboxamide | MLS000123376 | SMR000123976 | cid_3214781
Type:
Small organic molecule
Emp. Form.:
C18H21ClN2O4S
Mol. Mass.:
396.888
SMILES:
Cc1ccc(cc1Cl)S(=O)(=O)N1CCCC(C1)C(=O)NCc1ccco1
Structure:
Search PDB for entries with ligand similarity: