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Target
Tyrosine-protein phosphatase YopH
Ligand
BDBM42237
Substrate
n/a
Meas. Tech.
YopH - IC50 determinations (10 point dose range)
IC50
15024.90997±n/a nM
Citation
 PubChem, PC YopH - IC50 determinations (10 point dose range) PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase YopH
Synonyms:
YOPH_YEREN | yop51 | yopH
Type:
PROTEIN
Mol. Mass.:
50951.99
Organism:
Yersinia enterocolitica
Description:
ChEMBL_965525
Residue:
468
Sequence:
MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
  
Inhibitor
Name:
BDBM42237
Synonyms:
3'-(1-naphthalenyl)spiro[indene-2,2'-oxirane]-1,3-dione | 3'-(1-naphthyl)spiro[indane-2,2'-oxirane]-1,3-quinone | 3'-naphthalen-1-ylspiro[indene-2,2'-oxirane]-1,3-dione | MLS000592199 | SMR000218415 | cid_3742880
Type:
Small organic molecule
Emp. Form.:
C20H12O3
Mol. Mass.:
300.3075
SMILES:
O=C1c2ccccc2C(=O)C11OC1c1cccc2ccccc12
Structure:
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