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Target
Tyrosine-protein phosphatase YopH
Ligand
BDBM42205
Substrate
n/a
Meas. Tech.
YopH - IC50 determinations (10 point dose range)
IC50
>50000±n/a nM
Citation
 PubChem, PC YopH - IC50 determinations (10 point dose range) PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase YopH
Synonyms:
YOPH_YEREN | yop51 | yopH
Type:
PROTEIN
Mol. Mass.:
50951.99
Organism:
Yersinia enterocolitica
Description:
ChEMBL_965525
Residue:
468
Sequence:
MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
  
Inhibitor
Name:
BDBM42205
Synonyms:
5-[(E)-2-(4-chloroanilino)ethenyl]-3-(methylthio)-4-isothiazolecarbonitrile | 5-[(E)-2-(4-chloroanilino)ethenyl]-3-methylsulfanyl-1,2-thiazole-4-carbonitrile | 5-[(E)-2-(4-chloroanilino)vinyl]-3-(methylthio)isothiazole-4-carbonitrile | 5-[(E)-2-[(4-chlorophenyl)amino]ethenyl]-3-methylsulfanyl-1,2-thiazole-4-carbonitrile | 5-[2-(4-chloroanilino)vinyl]-3-(methylsulfanyl)-4-isothiazolecarbonitrile | MLS000539457 | SMR000125115 | cid_5524312
Type:
Small organic molecule
Emp. Form.:
C13H10ClN3S2
Mol. Mass.:
307.822
SMILES:
CSc1nsc(CC=Nc2ccc(Cl)cc2)c1C#N |w:8.8|
Structure:
Search PDB for entries with ligand similarity: