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Target
Tyrosine-protein phosphatase YopH
Ligand
BDBM42231
Substrate
n/a
Meas. Tech.
YopH - IC50 determinations (10 point dose range)
IC50
>50000±n/a nM
Citation
 PubChem, PC YopH - IC50 determinations (10 point dose range) PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase YopH
Synonyms:
YOPH_YEREN | yop51 | yopH
Type:
PROTEIN
Mol. Mass.:
50951.99
Organism:
Yersinia enterocolitica
Description:
ChEMBL_965525
Residue:
468
Sequence:
MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
  
Inhibitor
Name:
BDBM42231
Synonyms:
MLS000584232 | N-[(2-hydroxy-2-isoamyl-5-methyl-hexanoyl)amino]-N-phenyl-carbamic acid methyl ester | N-[[2-hydroxy-5-methyl-2-(3-methylbutyl)-1-oxohexyl]amino]-N-phenylcarbamic acid methyl ester | SMR000203395 | cid_3432701 | methyl 2-[2-hydroxy-5-methyl-2-(3-methylbutyl)hexanoyl]-1-phenylhydrazinecarboxylate | methyl N-[[2-hydroxy-5-methyl-2-(3-methylbutyl)hexanoyl]amino]-N-phenylcarbamate | methyl N-[[5-methyl-2-(3-methylbutyl)-2-oxidanyl-hexanoyl]amino]-N-phenyl-carbamate
Type:
Small organic molecule
Emp. Form.:
C20H32N2O4
Mol. Mass.:
364.4791
SMILES:
COC(=O)N(NC(=O)C(O)(CCC(C)C)CCC(C)C)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: