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Target
Neuropeptide Y receptor type 1
Ligand
BDBM42435
Substrate
n/a
Meas. Tech.
Dose response cell-based screening assay for antagonists of neuropeptide Y receptor Y1 (NPY-Y1)
IC50
12050±n/a nM
Citation
 PubChem, PC Dose response cell-based screening assay for antagonists of neuropeptide Y receptor Y1 (NPY-Y1) PubChem Bioassay (2008)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM42435
Synonyms:
(4-methylphenyl)methyl 5-amino-2-phenyltriazole-4-carboxylate | (4-methylphenyl)methyl 5-azanyl-2-phenyl-1,2,3-triazole-4-carboxylate | 4-methylbenzyl 5-amino-2-phenyl-2H-1,2,3-triazole-4-carboxylate | 5-amino-2-phenyl-4-triazolecarboxylic acid (4-methylphenyl)methyl ester | 5-amino-2-phenyl-triazole-4-carboxylic acid (4-methylbenzyl) ester | MLS000729082 | SMR000307360 | cid_1504749
Type:
Small organic molecule
Emp. Form.:
C17H16N4O2
Mol. Mass.:
308.3345
SMILES:
Cc1ccc(COC(=O)c2nn(nc2N)-c2ccccc2)cc1
Structure:
Search PDB for entries with ligand similarity: